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WHO: Monkeypox cases in Europe have tripled in last 2 weeks

July 1, 2022 by www.sfgate.com Leave a Comment

LONDON (AP) — The World Health Organization’s Europe chief warned Friday that monkeypox cases in the region have tripled in the last two weeks and urged countries to do more to ensure the previously rare disease does not become entrenched on the continent.

Dr. Hans Kluge said in a statement that increased efforts were needed despite the U.N. health agency’s decision last week that the escalating outbreak did not yet warrant being declared a global health emergency.

“Urgent and coordinated action is imperative if we are to turn a corner in the race to reverse the ongoing spread of this disease,” Kluge said.

To date, more than 5,000 monkeypox cases have been reported from 51 countries worldwide, according to the U.S. Centers for Disease Control and Prevention. Kluge said the number of infections in Europe represents about 90% of the global total, noting that 31 countries in the WHO’s European region have now identified cases.

Kluge said data reported to the WHO show that 99% of cases have been in men — and that the majority of those have been in men that have sex with men. But he said there were now “small numbers” of cases among household contacts, including children. Most people reported symptoms including a rash, fever, fatigue, muscle pain, vomiting and chills.

Scientists warn anyone who is in close physical contact with someone who has monkeypox or their clothing or bedsheets is at risk of infection, regardless of their sexual orientation. Vulnerable populations like children and pregnant women are thought to be more likely to suffer severe disease.

About 10% of patients were hospitalized for treatment or to be isolated, and one person was admitted to an intensive care unit. No deaths have been reported.

Kluge said the problem of stigmatization in some countries might make some people wary of seeking health care and said the WHO was working with partners including organizers of gay pride events.

In the U.K., which has the biggest monkeypox outbreak beyond Africa, officials have noted the disease is spreading in “defined sexual networks of gay, bisexual, or men who have sex with men.” British health authorities said there were no signs suggesting sustained transmission beyond those populations.

A leading WHO adviser said in May that the spike in cases in Europe was likely tied to sexual activity by men at two rave parties in Spain and Belgium, speculating that its appearance in the gay and bisexual community was a “random event.” British experts have said most cases in the U.K. involve men who reported having sex with other men in venues such as saunas and sex clubs.

Ahead of gay pride events in the U.K. this weekend, London’s top public health doctor asked people who have symptoms of monkeypox, like swollen glands or blisters, to stay home.

WHO Europe director Kluge appealed to countries to scale up their surveillance and genetic sequencing capacities for monkeypox so that cases could be quickly identified and measures taken to prevent further transmission. He said the procurement of vaccines “must apply the principles of equity.”

The main vaccine being used against monkeypox was originally developed for smallpox and the European Medicines Agency said earlier this week it was beginning to evaluate whether the shot should be authorized for monkeypox. The WHO has said supplies of the vaccine, made by Bavarian Nordic, are extremely limited.

Some countries including the U.K. and Germany have already begun vaccinating people at high-risk of monkeypox; the U.K. recently widened its immunization program to offer the shot to mostly gay and bisexual men who have multiple sexual partners and are thought to be most vulnerable.

Until May, monkeypox had never been known to cause large outbreaks beyond Africa, where the disease is endemic in several countries and mostly causes limited outbreaks when it jumps to people from infected wild animals.

To date, there have been about 1,800 suspected monkeypox cases including more than 70 deaths in Africa. Vaccines have never been used to stop monkeypox outbreaks in Africa.

The WHO’s Africa office said this week that countries with vaccine supplies “are mainly reserving them for their own populations.”

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Pair of orcas targeting great white sharks off South Africa’s coast

June 30, 2022 by edition.cnn.com Leave a Comment

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(CNN) A pair of orcas drove great white sharks away from a stretch of South African coast after killing five sharks over just a few months in 2017, according to a new study.

Great whites used to dominate areas of the Gansbaai coast, around 100 kilometers (62 miles) east of Cape Town, but have been avoiding them in recent years, according to a paper published in the African Journal of Marine Science on Wednesday.
The Gansbaai coast was once a popular spot for great white shark spotting, but sightings have decreased markedly in recent years. The study used long-term sightings and tagging data to demonstrate that great whites have been driven away by the orcas, sometimes known as killer whales.

Researchers also analyzed five great white shark carcasses been found washed up on the shore, four with their nutrient-rich livers removed and one with its heart taken out as well. They all had wounds made by the same pair of orcas, which have likely killed more great whites, say researchers.

The study tracked 14 great whites over five and a half years, and found they fled the area when the orcas were there. The researchers believe that the sharks’ sense of fear sets off a fast, long-term mass migration when they know the predator is present.
Read More

Drone video shows surfers' very close encounter with great white shark

Drone video shows surfers’ very close encounter with great white shark

“Initially, following an orca attack in Gansbaai, individual great white sharks did not appear for weeks or months,” said study lead author Alison Towner, a senior white shark biologist at the Dyer Island Conservation Trust, in a news release.
Towner believes this is “large-scale avoidance,” similar to how wild dogs in the Serengeti avoid certain areas when lions are present.

“The more the orcas frequent these sites, the longer the great white sharks stay away,” she added.

A changing ecosystem

Before the orcas started attacking great whites, the sharks had only been absent from Gansbaai for one week in 2007 and three weeks in 2016.
Great whites may have doomed the biggest shark that ever lived, fossil teeth reveal

Great whites may have doomed the biggest shark that ever lived, fossil teeth reveal

This means the extended absences witnessed by researches are unprecedented, and it’s changing the ecosystem in the area.
Bronze whaler sharks have emerged as new mid-ranking predators in the area, said Towner.
“These bronze whalers are also being attacked by the orcas too, who are indicating a level of experience and skill in hunting large sharks,” said Towner, who added that cape fur seals are now preying on African penguins, which are endangered.
“That’s a top-down impact, we also have ‘bottom up’ trophic pressures from extensive removal of abalone, which graze the kelp forests these species are all connected through,” she added.
“To put it simply, although this is a hypothesis for now, there is only so much pressure an ecosystem can take, and the impacts of orcas removing sharks, are likely far wider-reaching.”

An ‘abrupt decline’

Towner also believes that orcas are increasingly prevalent off the coast of South Africa, and this particular pair might be part of a rare group of shark eaters.
“This change in both top predators’ behavior could be related to a decline in prey populations, including fishes and sharks, causing changes in their distribution pattern,” she said.
Has the great white shark really vanished from Cape Town's waters?

Has the great white shark really vanished from Cape Town’s waters?

The orcas focus on younger sharks, she said, which could have a bigger impact on vulnerable great white populations as the sharks grow slowly and mature late in life.
Researchers acknowledge that sea surface temperatures could also impact sightings of great whites, but “the immediate and abrupt decline in sightings at the beginning of 2017 and the extended and increasing periods of absence cannot be explained.”
Other explanations could include direct fishing of great whites or decreased numbers of prey due to fishing, they add, but although this may “potentially contribute to an overall decline in numbers of great whites in South Africa, they are unlikely to explain the sudden localized decline.”

Another 2016 study suggested that there were just a few hundred great white sharks left in South Africa, compared to earlier estimates of a few thousand.
In addition, DNA analysis of shark tissue showed that the genetic diversity of the South Africa whites is exceptionally low, making them more susceptible to external shocks like disease or environmental change.

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Pandemic warning: Hundreds of unknown microbes found that could spark outbreak

July 1, 2022 by www.express.co.uk Leave a Comment

India: Glacier collapses in Uttarakhand and causes flooding

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The researchers wrote: “Ice-entrapped modern and ancient pathogenic microbes could lead to local epidemics and even pandemics. “The Tibetan Plateau, which is known as the water tower of Asia, is the source of several of the world’s largest rivers, including the Yangtze, the Yellow River, the Ganges River and Yarlung Tsangpo (Brahmaputra River). The release of potentially hazardous bacteria could affect the two most populated countries in the world: China and India .”

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In their study, geoscientist Dr Yongqin Liu of the Chinese Academy of Sciences and her colleagues took samples of ice from 21 glaciers across Asia’s Tibetan Plateau.

Often dubbed “the Roof of the World”, this vast region — the world’s highest plateau and the largest found above sea level — is sandwiched between the Taklamakan Desert to the north and the Himalayan mountain range to the south.

The researchers sequenced the DNA of all the microorganisms they found held within their ice samples, creating a genomic database they call the “Tibetan Glacier Genome and Gene” catalogue, or “TG2G” for short.

The researchers wrote: “Glaciers have traditionally been considered extreme environments.”

They are challenging to lifeforms, they added, “in terms of limited carbon resources, low temperature, frequent freeze–thaw cycles and strong ultraviolet radiation.”

A Tibetan glacier, left, and bacteria, right

Hundreds of previously-unknown and potentially infectious microbes were found in Tibetan glaciers (Image: Getty Images)

A topographic map of the Tibetan plateau

The Tibetan Plateau lies between the Taklamakan Desert and the Himalayan mountain range (Image: Creative Commons / Darekk2 / GLOBE / ETOPO1)

Nevertheless, the team identified 986 microbial species from within the glaciers — mostly bacteria, but also algae, archaea and fungi — around 82 percent of which were previously unknown to science.

This is not the first time the glaciers of Tibet have yielded such surprises. A study of ice cores from a single glacier back in early 2020 detected 33 different groups of viruses within the samples — 28 of which had never before been seen.

The creation of the catalogue, the team said, “is particularly timely as the glacier ecosystem is threatened by global warming, and glaciers are retreating at an unprecedented rate.

“Glacier retreat enhances nutrient and microorganism release into downstream ecosystems.”

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The Yangtze River Gorge in Sichuan, China

The Tibetan Plateau is the source of several of the world’s largest rivers, including the Yangtze (Image: Getty Images)

A map showing the sampling sites

The researchers took samples of ice from 21 glaciers across Asia’s Tibetan Plateau (Image: Liu et al. / Nature Biotechnology)

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From the catalogue, the researchers identified 27,000 potential “virulence factors” — cellular structures, molecules and regulatory systems that help bacteria colonise hosts.

Of these, 47 percent were distinct from known virulence factors, meaning that it is unclear at present how infectious these bacteria might be.

Many of the factors, the team explained, “were associated with mobile genetic elements that could enable their spread to other bacteria in downstream rivers, lakes and soils upon thawing.

“Enhanced meltwater discharge can increase the chance of these virulence factors interacting with local plants, animals and humans

“Further analyses of these factors are needed to evaluate the impact of global warming on water quality.”

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Graphs on the virulence factor diversity

From the catalogue, the researchers identified 27,000 potential ‘virulence factors’ (Image: Liu et al. / Nature Biotechnology)

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The findings may not all be doom and gloom, however — with the catalogue offering a permanent record of these bacteria that can be used for so-called bioprospecting.

This is the practice of hunting for organisms that have useful properties that can be harnessed — for example in the creation of new pharmaceuticals or even other products like cosmetics.

The creation of the TG2G database means that, even if the glaciers do one day melt and their microbial communities are lost, we may still be able to learn from them.

The full findings of the study were published in the journal Nature Biotechnology .

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Black Death ‘Big Bang’ site located by scientists chasing origin of killer plague

July 1, 2022 by www.dailystar.co.uk Leave a Comment

Scientists believe they have finally narrowed down the “Big Bang” site of the notorious Black Death , which killed an estimated 50 million people .

Historians have been plagued with questions over the origins of the infamous disease, but appear to have narrowed down their search even further with a massive breakthrough.

Researchers believe they have found the genetic ancestor of the Black Death, which still infects thousands of people each year.

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Biological evidence published by those same scientists have revealed the location of the virus’ origins, which were responsible for the Black Death and the millions it killed in the 13th century.

The terrifying plague which gave millions gangrenous, blackened lesions all over their body has been traced back to Central Asia, where scientists believe is the origin point for the virus.

Researcher Phil Slavin said that the virus, found in Kyrgyzstan “gave rise to the majority of [modern plague] strains circulating in the world today”.

Although they’ve figured out the Big Bang area of the disease, pinpointing when and where it happened is proving rather difficult.

Clues as to the location of the Black Death origins date back to as early as 1885, with DNA testing from human remains at a cemetery used as a marker for the plague’s location.

Despite the ground-breaking discovery and research from Slavin, one expert who was not involved in the study has said pinpointing a time of origin would be “nebulous”, NPR reported.

Hendrik Poinar said: “I would be very cautious about stretching it that far. Pinpointing a date and a specific site for emergence is a nebulous thing to do.”

But Poinar praised the research for narrowing down the search to this area of the world, marking it as a huge moment in piecing together the “plague puzzle”.

He added: “There was plague at that site 10 years prior to the strains that were circulating in western Europe, and I think that’s an important part of the plague puzzle.”

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How the Northern Territory is helping pave the way for better abortion access

July 1, 2022 by www.abc.net.au Leave a Comment

After the overturning of Roe v Wade in the United States cast a spotlight on reproductive rights in Australia, the Northern Territory has emerged as a leader in safe abortion access .

While a similar court ruling could never happen here, existing barriers to abortion and differing legislation among the states and territories have meant it wasn’t always easy to terminate a pregnancy.

So what makes abortion care so successful in the Northern Territory?

How the territory compares

Despite its large and hard-to-reach remote population, the Northern Territory offers women easier access to abortions than most Australian states and territories, according to MSI Australia’s latest abortion access scorecard .

MSI Australia’s managing director, Jamal Hakim, said: “The good story here is the Northern Territory is doing really well.”

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“[Remote living] is certainly one of the major challenges in the Northern Territory, and in healthcare generally.

“But we’re seeing medical abortions via telehealth, for example, as a really critical way of enabling that access.”

Over the border, Western Australia’s abortion laws are among the most restrictive in the country, and still fall under the state’s criminal code.

What are the abortion laws in the territory?

In November last year, the Northern Territory government passed legislation making it easier for women, girls and gender-diverse people to terminate a pregnancy in their second trimester.

The changes mean:

  • pregnant women can get an abortion between 14 and 24 weeks , in consultation with one doctor
  • pregnant women can legally get an abortion after 24 weeks for medical reasons , with support from two doctors.

Previously, it was illegal to terminate a pregnancy after 23 weeks in the Northern Territory unless it was ruled necessary to save a pregnant woman’s life.

Support offered to remote women

Family Planning NT chief executive Robin Wardle said “the Northern Territory is really a gold standard”.

She said that women in remote communities could access abortion services by visiting their local clinic, where they would be referred to a city centre, such as Darwin, Katherine, Alice Springs or Nhulunbuy, for the procedure.

In the territory, the cost of a medical abortion is free if you hold an Australian Medicare Card.

And, in some cases, the Northern Territory government will also help cover travel costs, such as when a pregnant woman or girl needs to be air-lifted to the nearest abortion clinic hundreds of kilometres away.

Ms Wardle said the territory’s system was so successful that Family Planning NT typically received “hundreds of calls every week” from women all over Australia seeking an abortion.

“We get calls about our termination services from Tasmania, Broome, everywhere,” she said.

Unplanned pregnancies happen

Medical anthropologist — and associate professor at the Menzies school of health research — Suzanne Belton said many women seeking abortions already had children.

“In all of the data I’ve ever seen, more than half of women going for abortions are already mothers, which means they’ve already completed their family,” Dr Belton said.

“Women don’t always want to be mothers, or they’d like to be mothers to only a small number of children and offer those children optimal opportunities.”

In Australia, more than a quarter of pregnancies are unplanned, and almost one third of those pregnancies end in abortion, according to a 2018 study conducted by Melbourne researchers.

“There’s no such thing as perfect contraception,” Dr Belton said.

“You have to be well organised, you have to have money — because you have to pay for contraception, it’s not free — and you have to be able to tolerate it in your body as well.”

Trends in the territory

About 60 per cent of women seeking abortions at the Northern Territory’s Family Planning clinics in Coconut Grove or Palmerston are at the six- or seven-week gestation mark, Ms Wardle said.

Up until nine weeks’ gestation, women in Australia typically have the option of taking medication to end a pregnancy instead of undergoing surgery.

Ms Wardle estimated that about 1,000 abortions were performed territory-wide each year.

In the less-common cases of later-term surgical abortions, Dr Belton said, some women simply didn’t realise they were pregnant or needed more time to decide.

Dr Belton said others were dealt the heartbreaking news that their baby had developed serious birth defects after seeing the results of genetic testing, which usually happens at 18 weeks.

Sometimes, abortion is the only way for a pregnant person to survive.

Women with kidney problems or rheumatic heart disease can suffer serious health complications, while others can die from an ectopic pregnancy or miscarriage if left untreated.

Areas of improvement

Mr Hakim said the Northern Territory could improve its abortion access even further by allowing nurses, midwives and Aboriginal health workers — not just doctors — to provide medical abortions.

That would remove a significant barrier facing remote Territorians, who need to travel long distances to terminate a pregnancy, he said.

“The Northern Territory is relying heavily on individual surgical abortion providers and health workers in the Royal Darwin Hospital to fill those gaps,” Mr Hakim said.

“But there’s so much more to do across the health system.”

Posted 1h ago 1 hours ago Fri 1 Jul 2022 at 10:50pm
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